Polybrene (hexadimethrine bromide)
Hexadimethrine Bromide - Polybrene Transduction Enhancer - Poly(hexamethylene biguanide) bromide - Quaternary ammonium polymer
Polybrene, also known as hexadimethrine bromide, is a cationic polymer widely used in cell culture and molecular biology applications. It enhances the efficiency of viral transduction by neutralizing charge repulsion between viral particles and the cell surface, thereby improving gene delivery outcomes.
- Chemical Name : Hexadimethrine bromide
- Common Name : Polybrene
- CAS Number : 28728-55-4
- Molecular Formula : (C₁₃H₂₆N₂)ₙ · Br⁻
- Appearance : White to off-white powder
- Solubility : Soluble in water
- For research use only
- Store at 2–8 °C in a dry environment
- Prepare fresh solutions or aliquot and freeze to avoid repeated freeze-thaw cycles
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